Male pattern baldness has been a natural ageing concern for men for all time, but despite this, a cure has never been found. However, in recent years there’s been a few promising breakthroughs in male pattern baldness research, which may have brought us closer to a cure.
By focusing on learning more about the hair growth cycle, researchers are hoping to finally get to the cause of the condition, rather than simply treating its symptoms. So, what new breakthroughs have been discovered and could they help produce a permanent male pattern baldness cure?
Cell therapy – early studies prove promising
Regenerative therapies have become the most recent potential cure to be researched. Early studies of the RepliCel Life Sciences regenerative therapies have been successful, proving the product is both safe and effective. This has led them to apply for, and be accepted a patent in the US for the technology used to provide these new cell therapies for male pattern baldness.
The RCH-01 autologous cell therapy is being trialled for use as a male and female pattern baldness treatment. It works by reversing damage caused by the sun and skin ageing, meaning it could also be used for skin rejuvenation procedures.
The cell therapy isn’t the only male pattern baldness treatment the Vancouver company is working on. It was announced in April, they have also been provided a patent in the US for their revolutionary device; a multi-needle dermal injection. Once fully tested and developed, RepliCel Life is planning on using both the device and cell therapy to treat male pattern baldness.
Topical compound could be developed thanks to KROX20 Protein discovery
Another recent development in hair loss research, is the discovery of the KROX20 Protein. This was discovered by researchers of the University of Texas Southwestern Medical Centre, situated in Dallas.
The protein is responsible for stimulating skin cells and converting them into hair. The cells once stimulated, also produce a protein responsible for hair pigmentation – SCF (Stem Cell Factor).
The researchers found that when they eliminated the SCF gene in mice, the hair started to grow grey, eventually turning white with age. They then experimented by eliminating the cells responsible for producing the KROX20 Protein. It was then that they discovered this caused the hair to not only stop growing, but for it to completely fall out.
The results of this study have given researchers the knowledge required to produce a potential topical treatment. It would deliver the genes required by the body to aid in healthy hair growth and colour.
The next step before a treatment can be produced, is looking into the link between KROX20 Protein and SCF in humans. The researchers will aim to discover whether male pattern baldness is triggered due to a problem with the function of SCF and the KROX20 Protein.
These are just two exciting developments that have been made recently in the hair loss field. As more scientific facts about hair loss are revealed, it does bring us much closer to developing a potential cure. In the meantime, however, there are clinically proven treatments available to help manage male pattern baldness.